个人简介

王玉先，博士，师资博士后

联系方式

办公地点：尚德楼B1-411

电子邮箱：yxwang@njtech.edu.cn

教育背景

2008.09-2011.06：荆楚理工学院化工与药学院，石油化工专业

2015.09-2018.06：万博体育bet 化学与分子工程学院，资源科学与工程专业，工学硕士

2018.09-2022.06：万博体育bet 生物与制药工程学院，制药工程与技术专业，工学博士

工作经历

2012.07-2015.08：丰益（上海）生物技术研发中心有限公司，研发技术员

2022.09-至今：万博体育bet 食品与轻工学院，师资博士后

奖励与荣誉

2018年6月在万博体育bet 被评为“优秀毕业研究生”

2022年6月在万博体育bet 被评为“校优秀博士学位论文”

研究方向

研究方向主要定位于食品营养与安全领域，聚焦纳米材料与微生物的互作关系，利用纳米材料对食源性致病菌的抗菌效应解决食品安全问题，同时利用纳米材料对肠道益生菌的递送作用解决肠道健康问题，具体研究内容如下：

1）金属基纳米材料的体内外抗菌效应的研究；

2）生物基微纳米材料的肠道靶向递送；

主持项目

1）江苏省科研与实践创新计划：基于金纳米团簇的多功能纳米抗生素的构建及其抗菌应用（KYCX20_1033），2020年6月-2021年12月。

2）2020年万博体育bet 优秀博士学位论文培育计划，2020年12月-2021年12月。

代表性论文（截至2022年10月）

1)WangYuxian, Shen Bowen, Zhang Zhengyi, Chen Yao, Zhu Liying, Zhang Yangheng, Huang He, Jiang Ling. Multifunctional fluorescent gold nanoclusters with enhanced aggregation-induced emissions (AIEs) and excellent antibacterial effect for bacterial imaging and wound healing.Biomaterials Advances, 2022, 137, 212841.(工程技术2区,IF: 8.457)

2)Wang Yuxian, Malkmes Matthew Jay, Jiang Cheng, Wang Peng, Zhu Liying, Zhang Hongman, Zhang Yangheng, Huang He, Jiang Ling. Antibacterial mechanism and transcriptome analysis of ultra-small gold nanoclusters as alternative of harmful antibiotics against Gram-negative bacteria.Journal of Hazardous Materials, 2021, 416, 126236.(环境科学与生态学1区,IF: 14.224)

3)Wang Yuxian, Dai Zijie, Zhang Zhidong, Zhu Liying, Zhang Hongman, Huang He, Jiang Ling. Draft genome sequence of a multidrug-resistant Stenotrophomonas sp. B1-1 strain isolated from radiation-polluted soil and its pathogenic potential.Journal of Global Antimicrobial Resistance. 2021, 24, 121-123.(医学3区,IF: 4.349)

4)Wang Yuxian, Zhu Liying, Zhang Hongman, Huang He, Jiang Ling. Formulation of pH and temperature dual-responsive Picking emulsion stabilized by chitosan-based microgel for recyclable biocatalysis.Carbohydrate Polymers, 2020, 214, 116373.(化学1区,IF: 10.123)

5)Wang Yuxian, Fan Panpan, Zhu Liying, Zhuang Wei, Jiang Ling, Zhang Hongman, Huang He. Enhanced in vitro antitumor efficacy of a polyunsaturated fatty acid-conjugated pH-responsive self-assemble ion-pairing liposome-encapsulated prodrug.Nanotechnology, 2020, 31, 155101.(材料科学3区,IF: 3.953)

6)Wang Yuxian, Jiang Ling, Wei Ce, Zhang Hongman. Phase behavior and self-assembled properties of ion-pairing amphiphile molecules formed by medium-chain fatty acids and L-arginine triggered by external conditions. New Journal of Chemistry, 2017, 41, 14486.(化学3区,IF: 3.925)

7)Wang Yuxian, Jiang Ling, Shen Qinke, Shen Jian, Han Yuwang, Zhang Hongman. Investigation on the self-assembled behaviors of C-18 unsaturated fatty acids in arginine aqueous solution. RSC Advances, 2017, 7, 41561.(化学3区,IF: 4.036)

8) Zhang Yangheng#, Wang Peng#,Wang Yuxian#, Li Jiao, Qiao Dan, Chen Rixin, Yang Wenrong, Yan Fuhua. Gold nanoparticles promote the bone regeneration of periodontal ligament stem cell sheets through activation of autophagy.International Journal of Nanomedicine, 2021, 16, 61.(医学2区, IF: 7.033) (共同一作)

9)ZhangYangheng#, Chen Rixin#,Wang Yuxian#, Wang Peng, Pu Jiajie, Xu Xiaoqiang, Chen Faming, Jiang Ling, Jiang Qing, Yan Fuhua. Antibiofilm activity of ultra-small gold nanoclusters against Fusobacterium nucleatum in dental plaque biofilms.Journal of Nanobiotechnology, In press.(工程技术2区,IF: 9.429) (共同一作)

10) Shen Bowen,Wang Yuxian, Wang Xinlong, Amal Fatima Ezzahra, Zhu Liying, Jiang Ling. A cruciform petal-like (ZIF-8) with bactericidal activity against foodborne Gram-positive bacteria for antibacterial food packaging.International Journal of Molecular Sciences, 2022, 14, 7510.(生物学2区,IF: 6.208)

11)王玉先,张红漫,朱丽英,江凌,黄和.金属纳米团簇的合成及抗菌效应的研究进展,生物加工过程,2022. 20 (1): 81-87.