主讲课程

生物分离工程、仪器分析

个人简介

杨朋朋，男，1988年，教授，硕士生导师。2016年毕业于万博体育bet 应汉杰院士门下，生物化工专业博士，化学工程与技术、材料科学与工程方向博士后，现在应汉杰院士团队。兼任国家生化工程技术研究中心主任助理、郑州大学“生物+”联合研究中心研究生导师、南京高新工大生物技术研究院技术顾问。

代表性成果

研究方向及主要科研成果：

（1）生化产品与化学品的分离精制、药物结晶；

（2）生物制造的工程化应用。

近5年于Chem. Eng. J.、ACS Sustainable Chemistry & Engineering、IUCRJ、Ultrason Sonochem、Journal of Chromatography A、Food Chem.、IECR、CrystEngComm等工程应用领域权威杂志发表论文20余篇，申请专利50余项，已获授权发明专利20余项。主持绿色生物制造国家重点研发计划课题、子课题、国家自然科学基金面上项目、青年项目等纵向横向项目10余项。获知识产权突出贡献奖、2021年江苏省教学成果二等奖

代表性论文：

1.Tao Shen, Bo Zhang, Yingying Wang,Pengpeng Yang*, Ming Li, Ruijia Hu, Kai Guo, Kequan Chen, Ning Zhu, Liang Wang, Chenjie Zhu*, Hanjie Ying. Production of 100% bio-based semi-aromatic nylon by aerobic oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid with bio aliphatic diamine,Chemical Engineering Journal, 2022, Volume 437, Part 1, 135361.

2.Pengpeng Yang,Xiaojie Li,Zihan Li,Xincao Fang,Keke Zhang*, Wei Zhuang, Jinglan Wu,Chenjie Zhu, Hanjie Ying. Green mechanochemical strategy for the construction of a new bio-based nylon 5₂4T ternary salt,ACS Sustainable Chemistry & Engineering,v 10, n 11, p 3513-3520, March 21, 2022.

3.Wei Zhuang,Zhenfu Wang,Wenfeng Zhou,Pengpeng Yang*,Lei Ge,Byron Villacorta Hernandez,Jinglan Wu,Ming Li,Chenjie Zhu,Hanjie Ying*, Interfacial microenvironment for lipase immobilization: Regulating the heterogeneity of graphene oxide,Chemical Engineering Journal, 2022,Volume 394, 125038.

4.Pengpeng Yang,Qingqing Li, Sen Wang; Wei Zhuang, Jingwei Zhou, Sha Zhu, Jinglan Wu*, Hanjie Ying*. Application of a humidity-mediated method to remove residual solvent from crystal lattice.Food Chemistry,2019, 294, 123-129.

5.Zhao, Jingjing#；Yang, Pengpeng#；Fu, Jinqiu；Wang, Yingying；Wang, Chiyi；Hou, Yihang；Shi, Yuzhong；Zhang, Keke*；Zhuang, Wei；Ying, Hanjie. Polymorph control by designed ultrasound application strategy: The role of molecular self-assembly,ULTRASONICS SONOCHEMISTRY, 2022(89):106118.

6.Pengfei Jiao*, Xin Zhang, Na Li, Yuping Wei, Peng Wang,Pengpeng Yang*, Cooperative adsorption of L-tryptophan and sodium ion on a hyper-cross-linked resin: Experimental studies and mathematical modeling,Journal of Chromatography A,2021, 1648, 462211.

7. Zihan Li, Shushu Li, Pengpeng Yang*, Xincao Fang, Qingshi Wen, Ming Li, Wei Zhuang, Jinglan Wu and Hanjie Ying.
The effect of polymorphism on polymer properties: Crystal structure, stability, and polymerization of a short-chain
bio-based nylon 52 monomer 1,5-pentanediamine-oxalate, IUCRJ,2022.

8.Pengpeng Yang,Chenguang Lin, Wei Zhuang, Qingshi Wen, Fengxia Zou, Jingwei Zhou, Jinglan Wu, Hanjie Ying*. Insight into a direct solid-solid transformation: a potential approach for the removal of residual solvents.CrystEngComm, 2016, 18 (10), 1699-1704.

9.Yang, Pengpeng; Wen, Qingshi;Wu, Jinglan; Zhuang, Wei; Zhang, Yuehui; Ying, Hanjie. Determination of Solubility of cAMPNa in Water plus (Ethanol, Methanol, and Acetone) within 293.15-313.15 K [J].Industrial & Engineering Chemistry Research, 2014, 53 (26), 10803-10809.

10.Haodong Liu,Pengpeng Yang*,Zihan Li, Qingshi Wen, Xiaojie Li, Chenjie Zhu, Pengfei Jiao, Wei Zhuang, Jinglan Wu, Hanjie Ying. Thermodynamics, Characterization, and Polymorphic Transformation of 1,5-Pentanediamine Carbonate.Industrial & Engineering Chemistry Research,2020, 59, (21), 10185-10194.

11.Pengpeng Yang,Xiaoqiang Peng, Sen Wang, Dong Li, Ming Li, Pengfei Jiao, Wei Zhuang, Jinglan Wu, Qingshi Wen*, Hanjie Ying*. Crystal structure, thermodynamics, and crystallization of bio-based polyamide 56 salt.Crystengcomm,2020, 22, (18), 3234-3241.

12.Pengpeng Yang, Junyang Jin, Qingshi Wen, Chenguang Lin, JinQiu Fu, Wei Zhuang, Jinglan Wu , Dong Liu*, Chenjie Zhu*, and Hanjie Ying. Hydrates of Adenosine 3’,5’-Cyclic Monophosphate Sodium and Their Transformation,Crystengcomm, 2021, 23 (1): 174-184.

13.Huifang Zhang†,Pengpeng Yang†,Zhenyu Wang,Mengting Li,Jie Zhang, Dong Liu*,Yong Chen* and Hanjie Ying, Clostridium acetobutylicum Biofilm: Advances in Understanding the Basis,Frontiers in Bioengineering and Biotechnology, 2021(9), 658568.

14.Zihan Li,Pengpeng Yang*,Handong Liu, Jun Liu, Sha Zhu, Xiaojie Li, Wei Zhuang, Jinglan Wu, Hanjie Ying. Crystal forms and phase transformation of 1,5-pentanediamine-terepnthalate: a bio-based nylon 5T monomer.Acta Crystallographica Section B-Structural Science Crystal Engineering and Materials,2020, 76, 524-533.

15.乔长晟，杨朋朋*，赵男等,基于代谢途径分析的多杀菌素高产菌株选育,《湖北农业科学》, 2013, 52(10):2309-2314.

代表性专利：

1.杨朋朋，应汉杰，李子涵等；戊二胺癸二酸盐及其晶体，专利号：ZL201810335906.7；

2.杨朋朋，应汉杰，林晨光等；一种二丁酰环磷腺苷钙盐的晶体，2018.7.16，中国，专利号：ZL 201810782011.8；

3.杨朋朋;李晓洁;应汉杰等;戊二胺制备过程中含硫酸钙固渣的处理方法,专利号ZL201910278349.4；

4.杨朋朋，林晨光，温庆仕等，5’-尿苷单磷酸晶体制备方法，专利号ZL202010999891.1；

5.应汉杰;杨朋朋;王森;吴菁岚;朱晨杰;许晟;陈可泉;陈勇;欧阳平凯；戊二胺己二酸盐及其晶体，PCT /CN2018/082438

6.应汉杰;杨朋朋;黎青青等；一种核苷酸混合物晶体粉末及其制备方法，专利号ZL201710980961.7；

7.应汉杰，杨朋朋，温庆仕等；一种从含有戊二胺的固相中汽提回收戊二胺的方法，ZL2019106923234；

8.应汉杰，杨朋朋，沈涛等；一种从含有戊二胺的水相中汽提回收戊二胺的方法，ZL201910692260.2;

9.应汉杰，李子涵，杨朋朋等；戊二胺丁二酸盐及其晶体，ZL201811201323.1；

10.应汉杰;李晓洁;杨朋朋等;一种戊二胺丁二酸对苯二甲酸共晶盐及其制备方法，ZL201911365842.6；

11.乔长晟;杨朋朋;赵男;蔡恒.产多杀菌素刺糖多孢菌及其培养和应用，专利号：ZL201110429550.1；

12.乔长晟;杨朋朋;李栋;蒋磊;赵男.一种利用活性污泥生产燃料乙醇的方法，授权公告号：CN102321723B，专利号：ZL201110207807.9；

代表性项目：

1.杨朋朋，生物制造关键共性技术开发与减碳，绿色生物制造国家重点研发计划课题，2022YFC2105402,2022.11.1- 2026.10.31，2050万，主持，在研；

2.杨朋朋，基于共结晶三元盐的生物基耐高温共聚酰胺链段结构调控新策略，国家自然科学基金面上项目，22278217, 2023.01- 2026.12，54万，主持，在研；

3.杨朋朋，国家自然科学基金-青年基金，环磷酸腺苷钠结晶水的形成机制与调控，21908100，23万，2020.1-2022.12，主持，在研；

4.杨朋朋，低廉生物质制备全生物基可降解包装材料关键技术，绿色生物制造国家重点研发计划子课题，SQ2022YFC210047，2023.01-2026.12，72万，主持，在研；

杨朋朋，江苏高校协同创新计划（先进生物制造协同创新中心）面上项目，XTD2207，虫草素与谷胱甘肽的高端化精制与产业应用，20万元，2021.1-2024.12，主持，在研；