报告题目：Study Bacteria Adhesion and Biofilm Development: Modelling and Experimental Characterisation

报告人：Jinju (Vicky) Chen 博士

邀请人：李鹏 教授

报告时间：1月7日（周一）10:00

报告地点：科技创新大楼C501室

Abstract

Bacteria-materials interactions are important for biofilm formation. The formation of biofilms has great impacts on a wide range of industries such as biomedical industries, marine industries and water industries. Therefore, it is important to understand how materials surface properties will affect bacteria attachment on surfaces and biofilm formation. In this study, the extended Derjaguin-Landau-Verwey-Overbeek (XDLVO) theory has been adopted to model how surface roughness and surface topography of materials as well as appendages of bacteria will affect bacteria attachment to material surfaces. These agree with experimental measurement. However, when it comes to nanostructured antimicrobial surface, the so-called surface roughness effect reinforced XDLVO model is not applicable which will be addressed in this talk.

In addition, an individual based model has also been developed to predict biofilm formation, and flow induced biofilm deformation, erosion and streamer formation. In this multiphysics computational model, bacteria growth, division, decay, mechanical contact between bacteria cells and adhesion between the bacteria-extracellular polymer substance, as well as flow shear force were implemented.

Biography

Dr Jinju (Vicky) Chenis a Senior Lecturer (Associate Professor) in Biointerface Engineering within School of Engineering at Newcastle University (Russell Group) .She established and led a research team with two ongoing post-doctoral research fellows (funded by EPSRC) and 9 PhD students. She is a Strategic Co-I and theme leader in Flow and Biomechanics for A New Frontier in Design: The Simulation of Open Engineered Biological Systems, one of the only five prestigious Frontier Awards (￡5.56 millions, 2013-2019) funded by EPSRC. She is also the PI for the ongoing EPSRC funded strategic equipment grant (￡0.49M, 2018-2020).

She completed her PhD thesis within 2 years and 9 months on nanomechanics and fracture mechanics of thin films. Then, she started working on cell mechanics, tissue engineering, bacteria physics, antimicrobial surfaces, biofilms mechanics and biofilm modelling. She is the Principal Editor of Journal of Materials Research and Guest Editor for Special Issue "Physics and Mechanics of Biofilms " in Processes. She is also an Editorial Board Member for Scientific Reports (Nature Publishing Group) in Biological Physics. She has given over 10 invited talks at major international conferences. She also organized and chaired over 10 sessions at major international conferences. She is also the external PhD examiner for the world-leading overseas Universities. She regularly reviews research grants for both UK research councils, French National Research Agency, Czech Republic Science Foundation and Singapore Research Council. Her web profile can be found below.

Web profile :https://www.ncl.ac.uk/engineering/staff/profile/jinjuchen.html#research