Dehydrative allylation of P-H species under metal-free conditions

Xiaobo Yang,^aBowen Li,^aHuicong Xing,^aJu Qiu,^aTeck-Peng Loh,^aband Peizhong Xie^a*

^aSchool of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, P. R. China.

bDivision of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.

Abstract:An environmentally benign protocol for C-P bond construction was developed under metal-and solvent-free conditions. In the presence of B(C₆F₅)₃, wide-spectrum P-H species, including dialkylphosphite, hypophosphite ester, and secondary phosphine oxides, can be successfully incorporated into the dehydrative cross-coupling process with allylic alcohols delivering the corresponding allylic organophosphorus compounds in high yields.

Green Chem.2021,23,1633-1637.（影响因子：10.182）

论文链接：https://pubs.rsc.org/en/content/articlepdf/2021/gc/d1gc00191d