张磊，女，1988年出生，分析化学博士，硕士生导师

邮箱：ias_lzhang@njtech.edu.cn

教育经历

2012.09-2015.09，南京大学,化学化工学院,理学博士,导师:鞠熀先,雷建平

2009.09-2012.06,厦门大学,化学化工学院,理学硕士,导师:李顺华

2005.09-2009.06,南京师范大学,化学与环境科学学院,理学学士

科研工作经历

2017.06-至今万博体育bet,化学与分子工程学院，副研究员

2018.12-2021.03德国慕尼黑大学（LMU），生物物理系，亚历山大・冯・洪堡学者，合作教授Thorben Cordes

2015.10-2017.05南京大学，化学化工学院，助理研究员

主持的科研项目

主持国家自然科学基金委面上项目和青年项目，江苏省科技厅青年项目，江苏省双创博士，江苏省高等学校自然科学面上项目

研究方向

方向一：荧光分子探针与生物传感

方向二：单分子光物理性能研究与超分辨荧光成像

代表性论文（仅包括以第一、通讯作者）

(1)Tong Zhou, Shuyan Zhang,Lei Zhang*, Tianyue Jiang, Haiyang Wang, Ling Huang, Hongshuai Wu, Zhining Fan, Su Jing*.Redox ferrocenylseleno compounds modulate longitudinal and transverse relaxation times of FNPs-Gd MRI contrast agents for multimodal imaging and photo-Fenton therapy.Acta Biomaterialia,2023,164, 496–510. (IF=10.633).

(2)Lei Zhang, Michael Isselstein, Jens Köhler, Nikoloas Eleftheriadis, Nadia Huisjes, Miguel Guirao, Alessandra Narducci, Jochem Smit, Janko Stoffels, Hartmann Harz, Heinrich Leonhardt, Andreas Herrmann,* Thorben Cordes.*Linker molecules convert commercial fluorophores into tailored functional probes during bio-labeling.Angewandte Chemie International Edition,2022,61, e202112959. (Cover paper,VIP and Hot,IF=16.823)

(3)Lei Zhang, Gill M. Biesold, Chunyan Zhao, Hui Xu, Zhiqun Lin, Necklace-like Nanostructures: from Fabrication, Properties to Applications.Advanced Materials,2022,34, 2200776.(IF=32.086)

(4)Lei Zhang,Fengjiao Ma,Jianping, Lei,*Jintong Liu,Huangxin Ju.*Target-triggered cascade assembly of catalytic network as artificial enzyme for highly efficient sensing.Chemical Science2017, 8, 4833–4839.(IF=9.969)

(5)YubanJi,^#Lei Zhang,^#LongyiZhu,Jianping Lei,*Jie Wu, Huangxian Ju. Binding-Induced DNA Walker for Signal Amplification in Highly Selective Electrochemical Detection of Protein.Biosensors & Bioelectronics2017,96, 201–205.(^#equalcontribution)(IF=12.545)

(6)Lei Zhang,Jianping Lei,*JintongLiu,Fengjiao Ma,Huangxian Ju.*In Situ Activating and Monitoring the Evolution of Intracellular Caspase Family.Chemical Science2015,6, 3365–3372.(IF=9.969)

(7)Lei Zhang,Jianping Lei,*JintongLiu,Fengjiao Ma,Huangxian Ju.*Persistent Luminescence Nanoprobe for Biosensing and Lifetime Imaging of Cell Apoptosis via Time-Resolved Fluorescence Resonance Energy Transfer.Biomaterials2015,67, 323–334.(IF=15.304)

(8)JintongLiu,^#Lei Zhang,^#Jianping Lei,*Huangxian Ju.*MicroRNA-Responsive Cancer Cell Imaging and Therapy with Functionalized Gold Nanoprobe.ACS Applied Materials & Interfaces2015,7, 19016–19023.(^#equalcontribution)(IF=10.383)

(9) Xiulian Lu, XuewenWang, Aimin Li, Tong Zhou,Lei Zhang*, Jian Qu, Zhijie Mao, Ximiao Gu, Xin Zhang, Su, Jing*,Ferrocenylseleno-dopamine functionalized carbon dots for redox-gated imaging and drug delivery in cancer cells.Dyes and Pigments,2022,205, 110586.

(10)Yeqiu Wang, Pengfei Dong, Jing Huang, Hui Xu,* Jianping Lei,*Lei Zhang.* Direct electrochemistry of silver nanoparticles-decorated metal-organic frameworks for telomerase activity sensing via allosteric activation of an aptamer hairpin,Analytica Chimica Acta,2021,1184, 339036.

(11)Huimin Xu, Yaqin Sang, Bin Xu, Li Zhang,Lei Zhang,* Hui Xu,* Immobilization of gold nanoparticles on poly(4-vinylpyridine)-grafted carbon nanotubes as heterogeneous catalysts for hydrogenation of 4-Nitrophenol,ACS Applied Nano Materials2020,3, 12169−12177.

(12)Michael Isselstein,^#Lei Zhang,^#Viktorija Glembockyte, Oliver Brix, Gonzalo Cosa, Philip Tinnefeld, Thorben Cordes.* Self-healing dyes—keeping the promise?The Journal of Physical Chemistry Letters2020,11, 4462−4480.(^#equalcontribution)

(13)Xianjiu Liao,^#Lei Zhang^#,Sina Wang,Jianping Lei.*Stepwise electrocatalytic reduction of nitric oxide by cationic picket-fence porphyrin in an ultrathin phospholipid film.Electrochemistry Communications,2019,100, 60−63.(^#equalcontribution)

(14)Lei Zhang,Jun Zhou, FengjiaoMa,Hui Xu, Huangxin Ju,*Jianping Lei.*Single-Sided Competitive Axial Coordination of G-Quadruplex/Hemin as Molecular Switch for Imaging Intracellular Nitric Oxide.Chemistry - A European Journal2019,25, 490−494.

(15)Fengjiao Ma,^#Lei Zhang,^#B. J. C.Wong,Jianping Lei.*In SituSimultaneous Profiling of Phosphorylation and Ubiquitination by Single Excitation-Duplexed Luminescence Resonance Energy Transfer.Chemical Communication2018,54, 3648–3651.(^#equal)

(16)Lei Zhang,Jianping Lei,*Fengjiao Ma,Pinghua Ling,Jintong Liu,Huangxian Ju.*A Porphyrin Photosensitized Metal−Organic Framework for Cancer Cell Apoptosis and Caspase Responsive Theranostics.Chemical Communication2015,51, 10831–10834.

(17)Lei Zhang,Yan Cheng, Jianping Lei,*Yuting Liu, Qing Hao,Huangxian Ju.Stepwise Chemical Reaction Strategy for Highly Sensitive Electrochemiluminescent Detection of Dopamine.Analytical Chemistry2013,85, 8001−8007.

(18)Lei Zhang,Jianping Lei,*Lin Liu,Changfeng Li, Huangxian Ju.Self-Assembled DNA Hydrogel as Switchable Material for Aptamer-Based Fluorescent Detection of Protein.Analytical Chemistry2013,85, 11077–11082.