个人简历

2017至今 万博体育bet ，先进化学制造研究院，副教授

2015-2017新加坡国立大学，化学与生物分子工程系，Research Fellow

2009-2014新加坡国立大学，化学系，博士

2006-2009新加坡南洋理工大学，化学与生物化学系，硕士

1998-2005南开大学，化学系，学士；元素有机化学研究所，硕士

研究方向

化学生物学领域，利用有机合成开发化学工具，进而实现表征并操控生物体系。具体包括：

1) 发展新型荧光染料和分子荧光探针并应用于生物成像和活性检测；

2) 应用纳米制备和荧光成像技术研究药物传递；

3) 激酶靶向抑制剂设计、合成与测试。

代表性论文

1. Cai，X.; Duo Mao, D.; Wang,C.; Kong, D.;Cheng, X.;* and Liu, B.* Multifunctional Liposome: Bright AIEgen-Lipid Conjugate with Strong Photosensitization,Angew. Chem. Int. Ed.(2018),Doi：10.1002/anie.201809641. (*共同通讯)

2.Cheng, X.;^?Zhang, R.;^?Cai, X.;and Liu, B.* A Reusable and Naked-eye Molecular Probe with Aggregation-induced Emission (AIE) Characteristics for Hydrazine Detection.J. Mater. Chem. B,(2017), 5，3565-3571.(?共同一作)

3. Yuan, Y.; Xu, S.;Cheng, X.; and Liu, B.* Bioorthogonal Turn-On Probe Based on Aggregation-Induced Emission Characteristics for Cancer Cell Imaging and Ablation.Angew. Chem. Int. Ed., (2016), 55, 6457–6461.

4. Yuan, Y.;?Zhang, R.;?Cheng, X.;?Xu, S.; and Liu, B.* A FRET Probe with AIEgen as the Energy Quencher: Dual Signal Turn-on for Self-validated Caspase Detection.Chem. Sci., (2016), 7, 4245-4250. (?共同一作)

5.Cheng, X.; Li, L.; Uttamchandani, M.; Yao, S. Q.*, A Tuned Affinity-Based Staurosporine Probe for In Situ Profiling of Protein Kinases.Chem. Commun., (2014), 50, 2851-2853.

6.Cheng, X.; Li, L.; Uttamchandani, M.; Yao, S. Q.* In Situ Proteome Profiling of C75, a Covalent Bioactive Compound with Potential Anti-cancer Activities.Org. Lett., (2014), 16, 1414-1417

7. Ge, J.;Cheng, X.; Tan, L.P.; Yao, S. Q.*, Ugi Reaction-Assisted Rapid Assembly of Affinity-Based Probes against Potential Protein Tyrosine Phosphatases.Chem. Commun., (2012), 48, 4453-4455.

8. Shi, H.;Cheng, X.; Sze, S.K.; Yao, S. Q.*, Proteome Profiling Reveals Potential Cellular Targets of Staurosporine Using a Clickable Cell-Permeable Probe.Chem. Commun., (2011), 47, 11306-11308.

9.Cheng, X., Liu, X.*, Microwave-enhanced One-pot Synthesis of Diversified 3-Acyl-5-hydroxybenzofurans.J. Combin. Chem.(2007), 9, 906-8.

程夏民 副教授

Email:xiamin@u.nus.edu